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TAB2 antibody [3B5]

Anti-TAB2 antibody [3B5] used in Flow cytometry (FACS). GTX82751
Anti-TAB2 antibody [3B5] used in Western Blot (WB). GTX82751

Cat. No. GTX82751

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3B5

Isotype

 IgG1

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all TAB2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human TAB2 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TGF-beta activated kinase 1 (MAP3K7) binding protein 2 , CHTD2 , MAP3K7IP2 , TAB-2

Cellular Localization

Membrane,Cytoplasm, cytosol

Background

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TAB2 antibody [3B5] used in Flow cytometry (FACS). GTX82751

GTX82751 FACS Image

FACS analysis of HL-60 cells using GTX82751 TAB2 antibody [3B5].
Green : TAB2
Purple : negative control

Anti-TAB2 antibody [3B5] used in Western Blot (WB). GTX82751

GTX82751 WB Image

WB analysis of HEK293 (1) and TAB2(AA: 1-300)-hIgGFc transfected HEK293 (2) cell lysate using GTX82751 TAB2 antibody [3B5].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399