GeneTex

  • Country / Location Selection

United States (US)

TAB2 antibody [HL1712]

Recombinant antibody
Anti-TAB2 antibody [HL1712] used in IHC (Paraffin sections) (IHC-P). GTX637311
Anti-TAB2 antibody [HL1712] used in Western Blot (WB). GTX637311
Anti-TAB2 antibody [HL1712] used in Western Blot (WB). GTX637311

Cat. No. GTX637311

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL1712

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all TAB2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Predict Reactivity

Bovine, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human TAB2. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TGF-beta activated kinase 1 (MAP3K7) binding protein 2 , CHTD2 , MAP3K7IP2 , TAB-2

Cellular Localization

Membrane,Cytoplasm, cytosol

Background

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-TAB2 antibody [HL1712] used in IHC (Paraffin sections) (IHC-P). GTX637311

GTX637311 IHC-P Image

TAB2 antibody [HL1712] detects TAB2 protein at cytoplasm by immunohistochemical analysis.
Sample: Paraffin-embedded rat stomach.
TAB2 stained by TAB2 antibody [HL1712] (GTX637311) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-TAB2 antibody [HL1712] used in Western Blot (WB). GTX637311

GTX637311 WB Image

Whole cell extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with TAB2 antibody [HL1712] (GTX637311) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TAB2 antibody [HL1712] used in Western Blot (WB). GTX637311

GTX637311 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with TAB2 antibody [HL1712] (GTX637311) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

There are currently no references for TAB2 antibody [HL1712] (GTX637311). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for TAB2 antibody [HL1712] (GTX637311). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 399
$ 169
Custom Conjugations