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TAB2 antibody

Anti-TAB2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31692

Cat No. GTX31692

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P, ELISA

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203)

Specificity/Sensitivity

TAB2 antibody is human specific. TAB2 antibody is predicted not to cross-react with other TAB proteins.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TAB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TAB2.The immunogen is located within the last 50 amino acids of TAB2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TGF-beta activated kinase 1 (MAP3K7) binding protein 2 , CHTD2 , MAP3K7IP2 , TAB-2

Cellular Localization

Membrane,Cytoplasm, cytosol

Background

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TAB2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31692

GTX31692 IHC-P Image

IHC-P analysis of human brain tissue using GTX31692 TAB2 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf