GeneTex
United States (US)

TAB3 antibody

Anti-TAB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX31693

Cat No. GTX31693

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Positive Control

Human Kidney Tissue Slide

Specificity/Sensitivity

TAB3 antibody is human specific. TAB3 antibody is predicted not to cross-react with other TAB proteins.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TAB3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TAB3.The immunogen is located within amino acids 40 - 90 of TAB3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tgf-Beta Activated Kinase 1 (Map3K7) Binding Protein 3,Map3K7Ip3,Nap1,Tab3

Background

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
Anti-TAB3 antibody used in IHC (Paraffin sections) (IHC-P). GTX31693

GTX31693 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31693 TAB3 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329