GeneTex
United States (US)

TAK1 (phospho Thr171) antibody

Cat No. GTX108581

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application ELISA-Ag
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA-Ag Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

Synthetic peptide: 1:8,000
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Drosophila

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tgf-Beta Activated Kinase 1,Cg1388,Cg18492,D-Tak,D-Tak,D10,Dtak1,Dtak,Dtak1,Dmtak1,Dmel\Cg18492,Tak,Tak-1,Tak1,Tak,Tak 1,Dtak,Dtak-1,Dtak1,Dtak,Dtak1,Dtak1,Tak,Tak1,Tak1

Background

Component of a protein kinase signal transduction cascade. Mediator of TGF-beta signal transduction. Responsible for activation of the JNK MAPK pathway (basket, bsk and hemipterous, hep) in response to LPS. Component of the NF-kappa-B pathway; relish-mediated JNK inhibition involves proteasomal degradation of Tak1; certain targets of Relish that are induced during immune responses may facilitate destruction of Tak1 and switch off the JNK cascade. Participates in diverse roles such as control of cell shape and regulation of apoptosis.

Database

Research Area

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169