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TAK1 (phospho Thr171) antibody

Cat. No. GTX108581

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ELISA-Ag

Reactivity

 Drosophila
Package
100 μl ($399),
25 μl ($169)
See all TAK1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA-Ag Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Drosophila

Immunogen

Carrier-protein conjugated synthetic peptide surrounding phospho Thr171 of drosophila TAK1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10630073

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TGF-beta activated kinase 1 , CG1388 , CG18492 , D-TAK , D-tak , D10 , DTAK1 , DTak , DTak1 , DmTak1 , Dmel\CG18492 , TAK , TAK-1 , TAK1 , Tak , Tak 1 , dTAK , dTAK-1 , dTAK1 , dTak , dTak1 , dtak1 , tak , tak1

Background

Component of a protein kinase signal transduction cascade. Mediator of TGF-beta signal transduction. Responsible for activation of the JNK MAPK pathway (basket, bsk and hemipterous, hep) in response to LPS. Component of the NF-kappa-B pathway; relish-mediated JNK inhibition involves proteasomal degradation of Tak1; certain targets of Relish that are induced during immune responses may facilitate destruction of Tak1 and switch off the JNK cascade. Participates in diverse roles such as control of cell shape and regulation of apoptosis.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169