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TANK antibody

Anti-TANK antibody used in Western Blot (WB). GTX31740
Anti-TANK antibody used in IHC (Paraffin sections) (IHC-P). GTX31740
Anti-TANK antibody used in IHC (Paraffin sections) (IHC-P). GTX31740

Cat. No. GTX31740

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all TANK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Positive Control

Rat Spleen Tissue Lysate(GTX27945) , Human Kidney Tissue Lysate(GTX29995)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TANK antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TANK.The immunogen is located within amino acids 350 - 400 of TANK.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TRAF family member associated NFKB activator , I-TRAF , ITRAF , TRAF2

Cellular Localization

Cytoplasm

Background

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Database

Research Area

DATA IMAGES

Anti-TANK antibody used in Western Blot (WB). GTX31740

GTX31740 WB Image

WB analysis of human kidney tissue lysate using GTX31740 TANK antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-TANK antibody used in IHC (Paraffin sections) (IHC-P). GTX31740

GTX31740 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX31740 TANK antibody.
Working concentration : 10 μg/ml

Anti-TANK antibody used in IHC (Paraffin sections) (IHC-P). GTX31740

GTX31740 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX31740 TANK antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399