TBLR1 antibody [4F3-A8-D9]

Cat. No. GTX49189

Host	Mouse
Clonality	Monoclonal
Clone Name	4F3-A8-D9
Isotype	IgG1
Application	WB, ICC/IF, IHC-P
Reactivity	Human, Mouse
Package	100 μg ($399)

See all TBLR1 products

Datasheet
Document

View product citations for antibody GTX49189 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human TBLR1 protein fragments expressed in E.coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transducin beta like 1 X-linked receptor 1 , C21 , DC42 , IRA1 , MRD41 , TBLR1

Cellular Localization

Nucleus

Background

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]

Database

Gene ID: 79718 TBL1XR1
UniProt: Q9BZK7 TBL1XR1

Research Area

DATA IMAGES

GTX49189 IHC-P Image

IHC-P analysis of huma breast cancer using TBLR1 antibody.

GTX49189 WB Image

WB analysis of mouse brain, mouse heart and K562 lysates using TBLR1 antibody at a dilution of 1:1,000.

GTX49189 ICC/IF Image

ICC/IF analysis of HeLa cells using TBLR1 antibody at a dilution of 1:150.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 399

Qty