GeneTex
United States (US)

TBP antibody [1F6]

GTX34254_20170112_IHC-P_1_18121410_739.jpg
GTX34254_20170112_IHC-P_18121410_486.jpg

Cat No. GTX34254

Host Mouse
Clonality Monoclonal
Clone Name 1F6
Isotype IgG1
Application IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

38 kDa. ( Note )

Specificity/Sensitivity

TBP/TATA Binding Protein Mouse Monoclonal Antibody (1F6) detects endogenous levels of TBP/TATA Binding Protein
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant Protein

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tata-Box Binding Protein,Gtf2D,Gtf2D1,Hdl4,Sca17,Tfiid,Tbp

Background

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of trans

Database

Research Area

DATA IMAGES
GTX34254_20170112_IHC-P_1_18121410_739.jpg

GTX34254 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcinoma using TBP/TATA Binding Protein Mouse Monoclonal Antibody diluted at 1:200.

GTX34254_20170112_IHC-P_18121410_486.jpg

GTX34254 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Kidney Tissue using TBP/TATA Binding Protein Mouse Monoclonal Antibody diluted at 1:200.

Package List Price ($)
$ 319