TBP/TATA Binding Protein Mouse Monoclonal Antibody (1F6) detects endogenous levels of TBP/TATA Binding Protein
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Tata-Box Binding Protein,Gtf2D,Gtf2D1,Hdl4,Sca17,Tfiid,Tbp
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of trans
GTX34254 IHC-P Image
Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcinoma using TBP/TATA Binding Protein Mouse Monoclonal Antibody diluted at 1:200.
GTX34254 IHC-P Image
Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Kidney Tissue using TBP/TATA Binding Protein Mouse Monoclonal Antibody diluted at 1:200.