GeneTex

  • Country / Location Selection

United States (US)

TCL1A antibody

Anti-TCL1A antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16378
Anti-TCL1A antibody used in Western Blot (WB). GTX16378

Cat. No. GTX16378

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all TCL1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human TCL1A (NP_001092195.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

T cell leukemia/lymphoma 1A , TCL1

Cellular Localization

Cytoplasm,Nucleus,Microsome,Endoplasmic reticulum

Background

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-TCL1A antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16378

GTX16378 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX16378 TCL1A antibody.
Blue : DAPI

Anti-TCL1A antibody used in Western Blot (WB). GTX16378

GTX16378 WB Image

WB analysis of Ramos cell lysate using GTX16378 TCL1A antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

There are currently no references for TCL1A antibody (GTX16378). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for TCL1A antibody (GTX16378). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399