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TCR V gamma 1.1 antibody [2.11]

Cat No. GTX14669

Host

Armenian Hamster

Clonality

Monoclonal

Clone Name

2.11

Isotype

IgG

Application

FACS

Reactivity

Mouse
Package
250 μg ($289)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Assay dependent
Not tested in other applications.

Product Note

The 2.11 monoclonal antibody reacts with an epitope in the Cr4 domain of TCR Vγ1.1 (T cell receptor V gamma 1.1).

PROPERTIES

Form

Liquid

Buffer

0.2μm-filtered PBS (pH7)

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

3.13.1 T cell hybridoma

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

<0.002EU/μg (Determined by LAL gel clotting assay)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

T cell receptor gamma chain,TCRGV1S1,TCRGV2S1,TCRGV3S1,TCRGV5S3,Tcrg

Background

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase. [provided by RefSeq, Jul 2008]

Database

REFERENCE

There are currently no references for TCR V gamma 1.1 antibody [2.11] (GTX14669). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 289