GeneTex
United States (US)

TCR gamma + delta antibody [GL3] (FITC)

TCR-gamma-delta-antibody-GL3-FITC_FACS_GTX11467-1_18121411_857.jpg

Cat No. GTX11467

Host Hamster
Clonality Monoclonal
Clone Name GL3
Isotype IgG
Application FACS
Reactivity Mouse
APPLICATION

Application Note

For FACS: Use 1.0 ug to label 10^6 cells in. Protocols are available upon request.

Specificity/Sensitivity

Mouse TCR gamma/delta
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline containing 0.02% sodium azide and BSA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

C57BL/6J intraepithelial lymphocytes

Purification

Protein G affinity purified.

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CD3-DELTA Antibody , T3D Antibody , CD3D Antibody , CD3-GAMMA Antibody , CD3G Antibody , T3G Antibody

Cellular Localization

Plasma membrane

Background

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
DATA IMAGES
TCR-gamma-delta-antibody-GL3-FITC_FACS_GTX11467-1_18121411_857.jpg

GTX11467 FACS Image

Staining of splenic T cells using TCR gamma + delta: FITC antibody (GTX11467) and FITC hamster IgG isotype control.

Package List Price ($)
$ 319