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TDP43 antibody

Anti-TDP43 antibody used in Immunoprecipitation (IP). GTX32912
Anti-TDP43 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32912
Anti-TDP43 antibody used in IHC (Paraffin sections) (IHC-P). GTX32912
Anti-TDP43 antibody used in IHC (Paraffin sections) (IHC-P). GTX32912
Anti-TDP43 antibody used in Western Blot (WB). GTX32912

Cat No. GTX32912

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, IP
Reactivity Human, Mouse
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:100
IHC-P 1:50 - 1:100
IP 1:20 - 1:50
Not tested in other applications.

Calculated MW

45 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

TAR DNA binding protein , ALS10 , TDP-43

Cellular Localization

Nucleus,Cytoplasm

Background

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-TDP43 antibody used in Immunoprecipitation (IP). GTX32912

GTX32912 IP Image

IP analysis of SW620 cell lysate using GTX32912 TDP43 antibody.
IP reaction : 3μg antibody / 200μg cell lysate
Dilution : 1:500

Anti-TDP43 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32912

GTX32912 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX32912 TDP43 antibody.
Blue : DAPI

Anti-TDP43 antibody used in IHC (Paraffin sections) (IHC-P). GTX32912

GTX32912 IHC-P Image

IHC-P analysis of human esophagus tissue using GTX32912 TDP43 antibody.
Dilution : 1:200

Anti-TDP43 antibody used in IHC (Paraffin sections) (IHC-P). GTX32912

GTX32912 IHC-P Image

IHC-P analysis of human endometrium tissue using GTX32912 TDP43 antibody.
Dilution : 1:200

Anti-TDP43 antibody used in Western Blot (WB). GTX32912

GTX32912 WB Image

WB analysis of various samples using GTX32912 TDP43 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE
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