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TDP43 antibody

Anti-TDP43 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX48590
Anti-TDP43 antibody used in Western Blot (WB). GTX48590
Anti-TDP43 antibody used in IHC (Paraffin sections) (IHC-P). GTX48590
Anti-TDP43 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX48590
Anti-TDP43 antibody used in Western Blot (WB). GTX48590

Cat. No. GTX48590

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Zebrafish, Chicken, Xenopus, Primate
Package
50 μl ($399)
See all TDP43 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 2 μg/ml
ICC/IF 1:100 - 1:1000
IHC-P 1:250
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris-Glycine, 0.15M NaCl

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide to a C-terminal region [within residues 350-414] of the human TARDBP protein. [Swiss-Prot# Q13148]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TAR DNA binding protein , ALS10 , TDP-43

Cellular Localization

Nucleus,Cytoplasm

Background

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-TDP43 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX48590

GTX48590 ICC/IF Image

ICC/IF analysis of MCF-7 cells using GTX48590 TDP43 antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI

Anti-TDP43 antibody used in Western Blot (WB). GTX48590

GTX48590 WB Image

WB analysis of HeLa cell lysate using GTX48590 TDP43 antibody.

Anti-TDP43 antibody used in IHC (Paraffin sections) (IHC-P). GTX48590

GTX48590 IHC-P Image

IHC-P analysis of human placenta tissue using GTX48590 TDP43 antibody.
Dilution : 1:250
Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)

Anti-TDP43 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX48590

GTX48590 ICC/IF Image

ICC/IF analysis of human iPS derived neuron cells using GTX48590 TDP43 antibody.
Red : primary antibody
Blue : DAPI
Dilution : 1:200
Permibilization : 0.3% Triton X-100
Fixation : 4% PFA

Anti-TDP43 antibody used in Western Blot (WB). GTX48590

GTX48590 WB Image

WB analysis of cell ovreexpresing TDP43 lysate using GTX48590 TDP43 antibody.
Loading : 5μg

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399