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TEM8 antibody [200C1339(SB20)]

Anti-TEM8 antibody [200C1339(SB20)] used in Western Blot (WB). GTX13798
Anti-TEM8 antibody [200C1339(SB20)] used in IHC (Paraffin sections) (IHC-P). GTX13798
Anti-TEM8 antibody [200C1339(SB20)] used in Western Blot (WB). GTX13798
Anti-TEM8 antibody [200C1339(SB20)] used in IHC (Paraffin sections) (IHC-P). GTX13798

Cat. No. GTX13798

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 200C1339(SB20)

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μg ($419)
See all TEM8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 3 μg/ml
ICC/IF 1:10 - 1:500
IHC-P 2 - 5 μg/ml
Not tested in other applications.

Calculated MW

63 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This monoclonal antibody was developed by immunizing mice with a synthetic peptide containing amino acids 481-497 (CINFTRVKNNQPAKYPL) of human TEM8.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ANTXR cell adhesion molecule 1 , ATR , GAPO , TEM8

Cellular Localization

Cell membrane

Background

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-TEM8 antibody [200C1339(SB20)] used in Western Blot (WB). GTX13798

GTX13798 WB Image

WB analysis of cells overexpressing TEM8 lysate using GTX13798 TEM8 antibody [200C1339(SB20)].

Anti-TEM8 antibody [200C1339(SB20)] used in IHC (Paraffin sections) (IHC-P). GTX13798

GTX13798 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX13798 TEM8 antibody [200C1339(SB20)].
Dilution : 5 μg/ml

Anti-TEM8 antibody [200C1339(SB20)] used in Western Blot (WB). GTX13798

GTX13798 WB Image

WB analysis of human heart tissue lysate (in RIPA buffer) using GTX13798 TEM8 antibody [200C1339(SB20)].
Loading : 35μg
Dilution : 0.3 μg/ml

Anti-TEM8 antibody [200C1339(SB20)] used in IHC (Paraffin sections) (IHC-P). GTX13798

GTX13798 IHC-P Image

IHC-P analysis of human colon tissue using GTX13798 TEM8 antibody [200C1339(SB20)].
Dilution : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419