GeneTex
United States (US)

TEM8 antibody

GTX64680_20180530_WB_18121411_669.jpg
GTX64680_20180530_ICCIF_18121411_363.jpg

Cat No. GTX64680

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

63 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 84-333 of human ANTXR1 (NP_060623.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ANTXR1 Antibody , ATR Antibody

Background

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Database

DATA IMAGES
GTX64680_20180530_WB_18121411_669.jpg

GTX64680 WB Image

WB analysis of various samples using GTX64680 TEM8 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64680_20180530_ICCIF_18121411_363.jpg

GTX64680 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX64680 TEM8 antibody.
Blue : DAPI

Package List Price ($)
$ 319