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TENC1 antibody [C2C3], C-term

Anti-TENC1 antibody [C2C3], C-term used in Western Blot (WB). GTX108618

Cat. No. GTX108618

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Human, Mouse
Package
100 μl ($419),
25 μl ($169)
See all TENC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:10000
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

153 kDa. ( Note )

Positive Control

human TENC1-transfected 293T cells

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human TENC1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2038108

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tensin 2 , C1-TEN , C1TEN , TENC1

Cellular Localization

Cell junction , focal adhesion , Cell membrane; Peripheral membrane protein; Cytoplasmic side

Background

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-TENC1 antibody [C2C3], C-term used in Western Blot (WB). GTX108618

GTX108618 WB Image

TENC1 antibody detects TENC1 protein by western blot analysis.
293T mock transfected (-) or transfected with a construct expressing human TENC1 (+).
5 % SDS-PAGE
TENC1 antibody (GTX108618) dilution: 1:5000

REFERENCE

Application Reference

Uchio-Yamada K et al. Am J Physiol Renal Physiol 2020; 318 (6) : F1520-F1530 Tensin2 is important for podocyte-glomerular basement membrane interaction and integrity of the glomerular filtration barrier.
Application : IHC-Fr
Reactivity : Mouse
Jeong H et al. Sci Rep 2017; 7 (1) : 17777 inhibition of c1-ten ptpase activity reduces * resistance through irs-1 and ampk pathways.
Application : WB
Reactivity : Human
Koh A et al. Cell Signal 2014; Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 419
$ 169