*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , DDDDK-human TET1-transfected 293T , NT2D1 , NT2D1 nuclear extract
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.
Affinity purified by Protein G.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CXXC6 antibody, FLJ10839 antibody, FLJ41442 antibody, KIAA1676 antibody, LCX antibody, bA119F7.1 antibody, TET1 antibody, methylcytosine dioxygenase TET1 antibody, leukemia-associated protein with a CXXC domain antibody, ten-eleven translocation 1 gene protein antibody, CXXC-type zinc finger protein 6 antibody, CXXC zinc finger 6 antibody, tet oncogene 1 antibody, CXXC finger 6 antibody, ten-eleven translocation-1 antibody
Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.