GeneTex
United States (US)

TET2 antibody, Internal

GTX88329_1009_IHC-P_18121411_839.jpg

Cat No. GTX88329

Host Goat
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 2-6μg/ml

Note :

IHC-P
Human Spleen shows nuclear staining in select splenocytes.

Not tested in other applications.

Calculated MW

224 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88329-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3).

Predict Reactivity

Mouse, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-PHPQSNNDQQREGSF, from the internal region of the protein sequence according to NP_001120680.1; NP_060098.3.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tet Methylcytosine Dioxygenase 2,Kiaa1546,Mds,Tet2

Background

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES
GTX88329_1009_IHC-P_18121411_839.jpg

GTX88329 IHC-P Image

IHC-P analysis of human spleen using GTX88329 TET2 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 4µg/ml

Package List Price ($)
$ 329