*Optimal dilutions/concentrations should be determined by the researcher.
Human Spleen shows nuclear staining in select splenocytes.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88329-PEP).
This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3).
Mouse, Dog(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Peptide with sequence C-PHPQSNNDQQREGSF, from the internal region of the protein sequence according to NP_001120680.1; NP_060098.3.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Tet Methylcytosine Dioxygenase 2,Kiaa1546,Mds,Tet2
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]