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TFE3 antibody

Anti-TFE3 antibody used in Western Blot (WB). GTX66746
Anti-TFE3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66746

Cat. No. GTX66746

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TFE3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 133-178 of Human TFE3.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

transcription factor binding to IGHM enhancer 3 , RCCP2 , RCCX1 , TFEA , bHLHe33

Cellular Localization

Nucleus

Background

This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Database

Research Area

DATA IMAGES

Anti-TFE3 antibody used in Western Blot (WB). GTX66746

GTX66746 WB Image

WB analysis of various samples using GTX66746 TFE3 antibody.
Lane1 : Hela cell lysate
Lane2 : sp2/0 cell lysate
Lane3 : PC12 cell lysate
Dilution : 1:500

Anti-TFE3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66746

GTX66746 IHC-P Image

IHC-P analysis of human kidney carcinoma tissue using GTX66746 TFE3 antibody.
Left : Primary antibody
Right : Negative control
Dilution : 1:50

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399