GeneTex
United States (US)

TFPI antibody

GTX16395_20180530_ICCIF_18121410_904.jpg
GTX16395_20180530_WB_18121410_179.jpg

Cat No. GTX16395

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

35 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-224 of human TFPI (NP_001027452.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tissue Factor Pathway Inhibitor,Epi,Laci,Tfi,Tfpi1,Tfpi

Background

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX16395_20180530_ICCIF_18121410_904.jpg

GTX16395 ICC/IF Image

ICC/IF analysis of MCF-7 cell using GTX16395 TFPI antibody.
Blue : DAPI

GTX16395_20180530_WB_18121410_179.jpg

GTX16395 WB Image

WB analysis of various samples using GTX16395 TFPI antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319