GeneTex
United States (US)

TFPI antibody

GTX31885_1533_IHC-P_20180221_18121410_373.jpg
GTX31885_3032_WB_20180221_18121410_982.jpg
GTX31885_1534_IHC-P_20180221_18121410_446.jpg

Cat No. GTX31885

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Positive Control

Rat Small Intestine Tissue Lysate(GTX24038)

Specificity/Sensitivity

At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TFPI antibody was raised against a 13 amino acid peptide near the amino terminus of human TFPI.The immunogen is located within amino acids 70 - 120 of TFPI.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tissue Factor Pathway Inhibitor,Epi,Laci,Tfi,Tfpi1,Tfpi

Background

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX31885_1533_IHC-P_20180221_18121410_373.jpg

GTX31885 IHC-P Image

IHC-P analysis of rat small intestine tissue using GTX31885 TFPI antibody.
Working concentration : 5 μg/ml

GTX31885_3032_WB_20180221_18121410_982.jpg

GTX31885 WB Image

WB analysis of rat small intestine tissue lysate using GTX31885 TFPI antibody.
Working concentration : 1 μg/ml

GTX31885_1534_IHC-P_20180221_18121410_446.jpg

GTX31885 IHC-P Image

IHC-P analysis of rat small intestine tissue using GTX31885 TFPI antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329