APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Dilution |
0.2-2.5 ug/ml |
2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
human fetal muscle
PROPERTIES
Form
Liquid
Buffer
1x PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human TFR2
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
transferrin receptor 2 , HFE3 , TFRC2
Cellular Localization
Cell membrane; Single-pass type II membrane protein
Background
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Database
Research Area
DATA IMAGES
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GTX46553 IHC-P Image
IHC-P analysis of human skin tissue using GTX46553 TFR2 antibody at 10.0μg/ml.
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GTX46553 WB Image
WB analysis of human fetal muscle tissue using GTX46553 TFR2 antibody at 0.2-1μg/ml.
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REFERENCE
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REVIEW
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