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TGF beta 1 antibody [5D2]

Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272
Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272

Cat No. GTX34272

Host Mouse
Clonality Monoclonal
Clone Name 5D2
Isotype IgG1
Application IHC-P
Reactivity Mouse, Rat
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Specificity/Sensitivity

TGFβ1 Mouse Monoclonal Antibody (5D2) detects endogenous levels of TGFB1
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic Peptide of TGFβ1

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transforming Growth Factor Beta 1,Ced,Dpd1,Lap,Tgfb,Tgfbeta,Tgfb1

Background

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES
Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272

GTX34272 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Liver Tissue using Caspase-3 Mouse Monoclonal Antibody diluted at 1:200.

Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272

GTX34272 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain Tissue using TGFbeta1 Mouse Monoclonal Antibody diluted at 1:200.

REFERENCE
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REVIEW
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Package List Price ($)
$ 319