GeneTex

  • Country / Location Selection

United States (US)

TGF beta 1 antibody [5D2]

Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272
Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272

Cat. No. GTX34272

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5D2

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Mouse, Rat
Package
100 μl ($399)
See all TGF beta 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

synthetic peptide derived from TGFbeta1 at 310-390 aa.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CED,DPD1,LAP,TGFB,TGFB1,TGFbeta,transforming growth factor beta 1,TGF beta 1

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES

Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272

GTX34272 IHC-P Image

IHC-P analysis of rat brain tissue using GTX34272 TGF beta 1 antibody [5D2].
Dilution : 1:200

Anti-TGF beta 1 antibody [5D2] used in IHC (Paraffin sections) (IHC-P). GTX34272

GTX34272 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX34272 TGF beta 1 antibody [5D2].
Dilution : 1:200

REFERENCE

There are currently no references for TGF beta 1 antibody [5D2] (GTX34272). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for TGF beta 1 antibody [5D2] (GTX34272). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399