GeneTex
United States (US)

TGF beta 3 antibody

TGF-beta-3-antibody_IHC (Formalin-fixed paraffin-embedded sections)_GTX15537-1_18121411_523.jpg

Cat No. GTX15537

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IP
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at RT for 20 minutes. GTX15537 demonstrates cytoplasmic staining. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 47 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

47 kDa. ( Note )

Positive Control

Placenta
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide derived from the C-terminus of the precursor form of human TGF beta 3.

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transforming Growth Factor Beta 3,Arvd,Arvd1,Lds5,Rnhf,Tgf-Beta3,Tgfb3

Cellular Localization

Secreted

Background

Transforming Growth Factor beta 3 (TGF beta 3) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional, capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide.

Database

Research Area

DATA IMAGES
TGF-beta-3-antibody_IHC (Formalin-fixed paraffin-embedded sections)_GTX15537-1_18121411_523.jpg

GTX15537 IHC-P Image

Human Placenta stained with anti-Transforming Growth Factor beta3 (TGFb3) antibody (GTX15537)