APPLICATION
Application Note
IHC-P: Use at a dilution of 1/100 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at RT for 20 minutes. GTX15537 demonstrates cytoplasmic staining. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 47 kDa. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Positive Control
Placenta
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide derived from the C-terminus of the precursor form of human TGF beta 3.
Purification
Immunogen affinity purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
transforming growth factor beta 3 , ARVD , ARVD1 , LDS5 , RNHF , TGF-beta3
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]
Database
Research Area
DATA IMAGES
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GTX15537 IHC-P Image
Human Placenta stained with anti-Transforming Growth Factor beta3 (TGFb3) antibody (GTX15537)
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REFERENCE
There are currently no references for TGF beta 3 antibody (GTX15537). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TGF beta 3 antibody (GTX15537). Be the first to share your experience with this product.
_GTX15537-1_w_23060620_934.webp "Anti-TGF beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX15537")
_GTX15537-1_w_23060620_934.webp "Anti-TGF beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX15537")