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TGF beta Receptor I antibody [3A11]

Anti-TGF beta Receptor I antibody [3A11] used in IHC (Paraffin sections) (IHC-P). GTX53107

Cat. No. GTX53107

Host

 Rat

Clonality

 Monoclonal

Clone Name

 3A11

Isotype

 IgG2

Application

 WB, IHC-P

Reactivity

 Mouse
Package
100 μg ($399)
See all TGF beta Receptor I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:800 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse ALK5 extra cellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane,Cell junction,Tight junction

Background

This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor I antibody [3A11] used in IHC (Paraffin sections) (IHC-P). GTX53107

GTX53107 IHC-P Image

IHC-P analysis of lung tissue sections from LPS exposed mouse using GTX53107 TGF beta Receptor I antibody [3A11].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399