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TGF beta Receptor I antibody [ARC55592]

Orthogonal
Anti-TGF beta Receptor I antibody [ARC55592] used in Western Blot (WB). GTX05030

Cat. No. GTX05030

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 ARC55592

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($419)
See all TGF beta Receptor I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:2000-1:8000
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50%Glycerol

Preservative

0.05% proclin300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TGF beta Receptor I (TGFBR1) (NP_004603.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AAT5,ACVRLK4,ALK5,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,TGFBR1,TGFR1,tbetaRI,transforming growth factor beta receptor 1,TGF beta Receptor 1,TGF beta Receptor I,TGF-beta receptor type-1

Cellular Localization

Cell membrane,Cell junction,Tight junction

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor I antibody [ARC55592] used in Western Blot (WB). GTX05030

GTX05030 WB Image

Orthogonal

WB analysis of various samples using GTX05030 TGF beta Receptor I antibody [ARC55592].
Dilution : 1:2000
Loading : 25μg

REFERENCE

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REVIEW

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Package List Price ($)
$ 419