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TGF beta Receptor I antibody

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX00839
Anti-TGF beta Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX00839
Anti-TGF beta Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX00839

Cat No. GTX00839

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat, Bovine
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:300-1:1000
ICC/IF Assay dependent
IHC-P 1:200-1:400
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Aqueous buffered solution, 1% BSA, 50% glycerol, 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human TGF-beta R1.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AAT5,ACVRLK4,ALK5,ESS1,LDS1,LDS1A,LDS2A,MSSE,SKR4,TGFBR1,TGFR1,tbetaRI,transforming growth factor beta receptor 1,TGF beta Receptor 1,TGF beta Receptor I,TGF-beta receptor type-1

Cellular Localization

Cell membrane,Cell junction,Tight junction

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX00839

GTX00839 WB Image

WB analysis of rat brain tissue lysate using GTX00839 TGF beta Receptor I antibody.
Lane 1 : rat brain lysates
Lane 2 : mouse embryo lysates
Dilution : 1:200

Anti-TGF beta Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX00839

GTX00839 IHC-P Image

IHC-P analysis of rat brain tissue using GTX00839 TGF beta Receptor I antibody.
Dilution : 1:200

Anti-TGF beta Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX00839

GTX00839 IHC-P Image

IHC-P analysis of human colon tissue using GTX00839 TGF beta Receptor I antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 319