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TGF beta Receptor I antibody

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX04547
Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX04547
Anti-TGF beta Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX04547

Cat. No. GTX04547

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat, Bovine
Package
100 μl ($399)
See all TGF beta Receptor I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1:5000
ICC/IF 1:50-1:200
IHC-P 1:200-1:400
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 1% BSA, 50% Glycerol

Preservative

0.03% Proclin300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human TGF-beta R1 (301-400aa)

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transforming growth factor beta receptor 1 , AAT5 , ACVRLK4 , ALK-5 , ALK5 , ESS1 , LDS1 , LDS1A , LDS2A , MSSE , SKR4 , TBR-i , TBRI , TGFR-1 , tbetaR-I

Cellular Localization

Cell membrane , Cell junction, tight junction , Cell surface

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX04547

GTX04547 WB Image

WB analysis of various tissue lysates using GTX04547 TGF beta Receptor I antibody.
Lane1 : Mouse placenta tissue lysate
Lane2 : Rat small intestine tissue lysate
Dilution : 1:1000

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX04547

GTX04547 WB Image

WB analysis of various tissue lysates using GTX04547 TGF beta Receptor I antibody.
Lane1 : Rat brain tissue lysate
Lane2 : Mouse embryo tissue lysate
Dilution : 1:200

Anti-TGF beta Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX04547

GTX04547 IHC-P Image

IHC-P analysis of rat brain tissue using GTX04547 TGF beta Receptor I antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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Package List Price ($)
$ 399