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TGF beta antibody [TB21]

Anti-TGF beta antibody [TB21] used in IHC (Paraffin sections) (IHC-P). GTX76527

Cat No. GTX76527

Host

Mouse

Clonality

Monoclonal

Clone Name

TB21

Isotype

IgG1

Application

WB, IHC-P, IHC-Fr, FACS, ELISA

Reactivity

Human, Mouse, Rat, Rabbit, Sheep, Bovine, Mink, Mustelid
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
ELISA Assay dependent
Not tested in other applications.

Specificity/Sensitivity

This antibody recognizes both human platelet-derived and recombinant TGF-beta1.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human Transforming Growth Factor Beta 1 from platelets.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

LAP Antibody , CED Antibody , TGFB1 Antibody , transforming growth factor, beta 1 Antibody , TGFB Antibody , DPD1 Antibody , TGFbeta Antibody

Background

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]

Research Area

DATA IMAGES

Anti-TGF beta antibody [TB21] used in IHC (Paraffin sections) (IHC-P). GTX76527

GTX76527 IHC-P Image

IHC analysis of human brain tissue using GTX76527 TGF beta antibody [TB21].

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399