TGFBI antibody [C1C3]

Name: TGFBI antibody [C1C3]
Brand: GeneTex
SKU: GTX100744
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-TGFBI antibody [C1C3] used in Western Blot (WB). GTX100744

Cat. No. GTX100744

Reference 4

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Chicken
Package	100 μl ($399), 25 μl ($169)

See all TGFBI products

View product citations for antibody GTX100744 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000

Not tested in other applications.

Calculated MW

75 kDa. ( Note )

Positive Control

HeLa

Predict Reactivity

Mouse, Rat, Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human TGFBI. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2038114

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transforming growth factor beta induced , BIGH3 , CDB1 , CDG2 , CDGG1 , CSD , CSD1 , CSD2 , CSD3 , EBMD , LCD1

Cellular Localization

Secreted , extracellular space , extracellular matrix

Background

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq]

Database

Gene ID: 7045 TGFBI
UniProt: Q15582 TGFBI

Research Area

DATA IMAGES

GTX100744 WB Image

Sample (30 μg of whole cell lysate)
A: HeLa
7.5% SDS PAGE
TGFBI antibody
GTX100744 diluted at 1:1000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX100744 WB Image

The data was published in the 2018 in Sci Rep. PMID: 29891991

REFERENCE

Application Reference

Tzu-Yin Lin et al. Cancers (Basel) 2022; 14 (5) EGFR Mutation-Harboring Lung Cancer Cells Produce CLEC11A with Endothelial Trophic and Tumor-Promoting Activities.

Application : WB

Reactivity : Human

Brzozowski JS et al. Sci Rep 2018; 8 (1) : 8822 Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion.

Application : WB

Reactivity : Human

Kosla J et al. Eur J Cell Biol 2013; 92 (12) : 363-73 Effective myofibroblast dedifferentiation by concomitant inhibition of TGF-β signaling and perturbation of MAPK signaling.

Kosla J et al. Gene 2013; 513 (1) : 90-100 Molecular analysis of the TGF-beta controlled gene expression program in chicken embryo dermal myofibroblasts.

Application : WB

Reactivity : Chicken

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REVIEW