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TGR5 antibody

Anti-TGR5 antibody used in IHC (Paraffin sections) (IHC-P). GTX12523

Cat. No. GTX12523

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
25 μg ($399)
See all TGR5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 9 μg/ml
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.87 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human TGR5.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

G protein-coupled bile acid receptor 1 , BG37 , G proteincoupled bile acid receptor 1 , GPBAR1 , GPCR19 , GPR131 , MBAR , TGR5 , GPCR TGR5

Cellular Localization

Cell membrane

Background

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TGR5 antibody used in IHC (Paraffin sections) (IHC-P). GTX12523

GTX12523 IHC-P Image

IHC-P analysis of human uterus, endometrium tissue using GTX12523 TGR5 antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399