*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Mouse, Rat, Rabbit, Bovine, Dog, Hamster, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.87 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human TGR5.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
G protein-coupled bile acid receptor 1 , BG37 , G proteincoupled bile acid receptor 1 , GPBAR1 , GPCR19 , GPR131 , MBAR , TGR5 , GPCR TGR5
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
GTX12523 IHC-P Image
IHC-P analysis of human uterus, endometrium tissue using GTX12523 TGR5 antibody.