APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 μg/mL |
| 2.5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
HepG2 Cell Lysate(GTX27900) , Human Liver Tissue Slide
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
THEM2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human THEM2.The immunogen is located within the last 50 amino acids of THEM2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
acyl-CoA thioesterase 13 , HT012 , PNAS-27 , THEM2
Cellular Localization
Cytoplasm, cytosol,Mitochondrion,Nucleus
Background
THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.
Database
Research Area
DATA IMAGES
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GTX85271 IHC-P Image
IHC-P analysis of human liver tissue using GTX85271 THEM2 antibody.
Working concentration : 2.5 μg/ml
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GTX85271 IHC-P Image
IHC-P analysis of human liver tissue using GTX85271 THEM2 antibody.
Working concentration : 20 μg/ml
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GTX85271 WB Image
WB analysis of HepG2 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX85271 THEM2 antibody.
Working concentration : 1 μg/ml
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REFERENCE
There are currently no references for THEM2 antibody (GTX85271). Be the first to share your publications with this product.
REVIEW
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