GeneTex

  • Country / Location Selection

United States (US)

TIA1 antibody

Anti-TIA1 antibody used in Western Blot (WB). GTX33545
Anti-TIA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33545
Anti-TIA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33545
Anti-TIA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33545
Anti-TIA1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33545

Cat. No. GTX33545

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TIA1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human TIA1 (NP_071505.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887719

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TIA1 cytotoxic granule associated RNA binding protein , TIA-1 , WDM

Cellular Localization

Nucleus

Background

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]

Database

Research Area

DATA IMAGES

Anti-TIA1 antibody used in Western Blot (WB). GTX33545

GTX33545 WB Image

WB analysis of BT-474 cell lysate using GTX33545 TIA1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TIA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33545

GTX33545 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX33545 TIA1 antibody.
Dilution : 1:100

Anti-TIA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33545

GTX33545 IHC-P Image

IHC-P analysis of rat brain tissue using GTX33545 TIA1 antibody.
Dilution : 1:100

Anti-TIA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33545

GTX33545 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX33545 TIA1 antibody.
Dilution : 1:100

Anti-TIA1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33545

GTX33545 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX33545 TIA1 antibody.
Blue : DAPI

REFERENCE

Application Reference

Yoshii M et al. Oncol Lett 2012; 4 (3) : 381-384 Systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease of childhood: Report of a case with review of the literature.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for TIA1 antibody (GTX33545). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399