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TIE1 antibody [12D9]

Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470

Cat No. GTX52470

Host

Mouse

Clonality

Monoclonal

Clone Name

12D9

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

Product Note

This antibody recognizes human Tie1 in western blot without cross reactivity with human Tie2.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

hTie1 extracellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

JTK14 , TIE , TIE1 , tyrosine kinase with immunoglobulin like and EGF like domains 1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Database

Research Area

DATA IMAGES

Anti-TIE1 antibody [12D9] used in IHC (Paraffin sections) (IHC-P). GTX52470

GTX52470 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52470 TIE1 antibody [12D9].

REFERENCE

There are currently no references for TIE1 antibody [12D9] (GTX52470). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TIE1 antibody [12D9] (GTX52470). Be the first to share your experience with this product.
SDS
PBS.pdf