*Optimal dilutions/concentrations should be determined by the researcher.
|1:500 - 1:1000
|1:1000 - 1:2000
Not tested in other applications.
This antibody recognizes human Tie2 in western blot without cross reactivity with human Tie1.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
200 μg/ml (Please refer to the vial label for the specific concentration.)
hTie2 extracellular domain
Protein G purified
From tissue culture supernatant
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
CD202B , TEK , TEK receptor tyrosine kinase , TIE2 , VMCM , VMCM1
Cell membrane,Cell junction,Focal adhesion,Cytoplasm,Cytoskeleton,Secreted
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]