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TIE2 antibody [21G7]

Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471

Cat No. GTX52471

Host

Mouse

Clonality

Monoclonal

Clone Name

21G7

Isotype

IgG1

Application

WB, IHC-P, ELISA

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P Assay dependent
ELISA 1:1000 - 1:2000
Not tested in other applications.

Calculated MW

126 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes human Tie2 in western blot without cross reactivity with human Tie1.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

hTie2 extracellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD202B , TEK , TEK receptor tyrosine kinase , TIE2 , VMCM , VMCM1

Cellular Localization

Cell membrane,Cell junction,Focal adhesion,Cytoplasm,Cytoskeleton,Secreted

Background

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Database

Research Area

DATA IMAGES

Anti-TIE2 antibody [21G7] used in IHC (Paraffin sections) (IHC-P). GTX52471

GTX52471 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52471 TIE2 antibody [21G7].

REFERENCE

There are currently no references for TIE2 antibody [21G7] (GTX52471). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TIE2 antibody [21G7] (GTX52471). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329