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TIE2 (phospho Tyr992) antibody

Anti-TIE2 (phospho Tyr992) antibody used in Western Blot (WB). GTX55336

Cat No. GTX55336

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
Package
100 μl ($319)
See all TIE2 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
Not tested in other applications.

Calculated MW

126 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y(p)-V-K) derived from human TIE2.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

TEK receptor tyrosine kinase,CD202B,GLC3E,TIE-2,TIE2,VMCM,VMCM1

Cellular Localization

Cell membrane,Cell junction,Cytoplasm, cytoskeleton,Secreted

Background

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Database

Research Area

DATA IMAGES
Anti-TIE2 (phospho Tyr992) antibody used in Western Blot (WB). GTX55336

GTX55336 WB Image

WB analysis of extracts from HepG2 cells using GTX55336 TIE2 (phospho Tyr992) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide
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Package List Price ($)
$ 319