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TIGIT antibody [HMV322] HistoMAX™

Recombinant antibody HistoMAX
Anti-TIGIT antibody [HMV322] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639946
Anti-TIGIT antibody [HMV322] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639946
Anti-TIGIT antibody [HMV322] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639946

Cat. No. GTX639946

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HMV322

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($649),
100 μl ($329)
See all TIGIT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Product Note

This antibody was raised against human TIGIT Intracellular domain.This antibody was raised against human TIGIT Intracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS, 2% BSA

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the Intracellular domain of human TIGIT. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

T cell immunoreceptor with Ig and ITIM domains,VSIG9,VSTM3,WUCAM

Cellular Localization

Cell membrane

Background

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-TIGIT antibody [HMV322] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639946

GTX639946 IHC-P Image

IHC-P analysis of human appendix mucosa tissue using GTX639946 TIGIT antibody [HMV322] HistoMAX™.
Distinct TIGIT staining of a subset of lymphocytes.

Anti-TIGIT antibody [HMV322] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639946

GTX639946 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX639946 TIGIT antibody [HMV322] HistoMAX™.
Most TIGIT positive lymphocytes are in the interfollicular area while the strongest TIGIT staining occurs in a subset of lymphocytes in the germinal centre.

Anti-TIGIT antibody [HMV322] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX639946

GTX639946 IHC-P Image

IHC-P analysis of human lymph node tissue using GTX639946 TIGIT antibody [HMV322] HistoMAX™.
Most TIGIT positive lymphocytes are in the interfollicular area while the strongest TIGIT staining occurs in the few labeled lymphocytes in a small germinal centre.

REFERENCE

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REVIEW

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Package List Price ($)
$ 649
$ 329
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