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TIM-3 antibody

Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX04872
Anti-TIM-3 antibody used in Western Blot (WB). GTX04872
Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX04872

Cat. No. GTX04872

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all TIM-3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Predict Reactivity

Dog, Horse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human HAVCR2(Accession Q8TDQ0), corresponding to amino acid residues K233-Y283.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD366,HAVCR2,HAVcr2,KIM3,TIM3,TIMD3,Tim3,hepatitis A virus cellular receptor 2,TIM-3

Cellular Localization

Membrane,Cell junction

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX04872

GTX04872 IHC-P Image

IHC-P analysis of human lung cancer and adjacent normal tissue using GTX04872 TIM-3 antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-TIM-3 antibody used in Western Blot (WB). GTX04872

GTX04872 WB Image

WB analysis of HepG2 whole cell lysate using GTX04872 TIM-3 antibody. The lane on the right was treated with blocking peptide.

Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX04872

GTX04872 IHC-P Image

IHC-P analysis of human mammary cancer tissue using GTX04872 TIM-3 antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 399