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TIM-3 antibody

Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX49381
Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX49381
Anti-TIM-3 antibody used in Western Blot (WB). GTX49381

Cat No. GTX49381

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TIM3 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TIM3. The immunogen is located within amino acids 60 - 110 of TIM3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

hepatitis A virus cellular receptor 2 , CD366 , HAVcr-2 , KIM-3 , TIM3 , TIMD-3 , TIMD3 , Tim-3

Cellular Localization

Membrane,Cell junction

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX49381

GTX49381 IHC-P Image

IHC-P analysis of human spleen tissue using GTX49381 TIM-3 antibody.
Dilution : 20 μg/ml

Anti-TIM-3 antibody used in IHC (Paraffin sections) (IHC-P). GTX49381

GTX49381 IHC-P Image

IHC-P analysis of human spleen tissue using GTX49381 TIM-3 antibody.
Dilution : 2 μg/ml

Anti-TIM-3 antibody used in Western Blot (WB). GTX49381

GTX49381 WB Image

WB analysis of Jurkat cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX49381 TIM-3 antibody.
Dilution : 1 μg/mL

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf