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TIM-4 antibody [RMT4-53]

Cat. No. GTX14149

Reference 2

Host

 Rat

Clonality

 Monoclonal

Clone Name

 RMT4-53

Isotype

 IgG2b

Application

 WB, ICC/IF, Neutralizing/Inhibition

Reactivity

 Mouse
Package
500 μg ($399)
See all TIM-4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse TIM-4-Ig fusion protein

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

RRID

AB_2887513

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Membrane

Database

Research Area

REFERENCE

Application Reference

Wu H et al. Cell Prolif 2020; 53 (1) : e12731 TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway.
Wu H et al. Int J Mol Med 2018; (Epub) TIM-4 blockade of KCs combined with exogenous TGF-β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts.
Application : WB, ICC/IF
Reactivity : Mouse
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Package List Price ($)
$ 399