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TIMP1 antibody

Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714
Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714
Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714
Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714
Anti-TIMP1 antibody used in Western Blot (WB). GTX03714
Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714

Cat. No. GTX03714

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat, Rabbit
Package
100 μl ($399)
See all TIMP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P 1:100-1:500
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 1% BSA, 50% Glycerol

Preservative

0.03% Proclin300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human TIMP-1 (103-207).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TIMP metallopeptidase inhibitor 1 , CLGI , EPA , EPO , HCI , TIMP , TIMP-1

Cellular Localization

Secreted

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714

GTX03714 IHC-P Image

IHC-P analysis of 4% PFA-fixed human gastric carcinoma tissue using GTX03714 TIMP1 antibody.
Antigen retireval : Citrate buffer (0.01M, pH 6.0) boiling for 15min
Dilution : 1:200

Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714

GTX03714 IHC-P Image

IHC-P analysis of rabbit liver tissue using GTX03714 TIMP1 antibody.
Dilution : 1:200

Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714

GTX03714 IHC-P Image

IHC-P analysis of human neurilemmoma tissue using GTX03714 TIMP1 antibody.
Antigen retireval : sodium citrate buffer (pH 6.0) boiling for 15min
Dilution : 1:500

Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714

GTX03714 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX03714 TIMP1 antibody.
Dilution : 1:200

Anti-TIMP1 antibody used in Western Blot (WB). GTX03714

GTX03714 WB Image

WB analysis of various sample lysates using GTX03714 TIMP1 antibody.
Lane 1 : Mouse brain
Lane 2 : Mouse Liver
Loading : 30μg
Dilution : 1:200

Anti-TIMP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX03714

GTX03714 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX03714 TIMP1 antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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Package List Price ($)
$ 399