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TIMP1 antibody

Anti-TIMP1 antibody used in Western Blot (WB). GTX64360
Anti-TIMP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64360
Anti-TIMP1 antibody used in Western Blot (WB). GTX64360

Cat. No. GTX64360

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all TIMP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-207 of human TIMP1 (NP_003245.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TIMP metallopeptidase inhibitor 1 , CLGI , EPA , EPO , HCI , TIMP , TIMP-1

Cellular Localization

Secreted

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TIMP1 antibody used in Western Blot (WB). GTX64360

GTX64360 WB Image

WB analysis of mouse lung tissue lysate using GTX64360 TIMP1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:3000
Loading : 25μg per lane

Anti-TIMP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64360

GTX64360 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX64360 TIMP1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-TIMP1 antibody used in Western Blot (WB). GTX64360

GTX64360 WB Image

WB analysis of various sample lysates using GTX64360 TIMP1 antibody.
Dilution : 1:3000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399