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TIMP2 antibody [2C13]

Anti-TIMP2 antibody [2C13] used in IHC (Paraffin sections) (IHC-P). GTX52487

Cat. No. GTX52487

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2C13

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all TIMP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Product Note

This antibody recognizes human TIMP-2 in western blot. No cross-reactivity to human TIMP-1 is noted.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant TIMP-2 protein

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CSC21K , DDC8 , TIMP metallopeptidase inhibitor 2 , TIMP2

Cellular Localization

Secreted

Background

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TIMP2 antibody [2C13] used in IHC (Paraffin sections) (IHC-P). GTX52487

GTX52487 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52487 TIMP2 antibody [2C13].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399