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TIMP2 antibody [2C13]

Anti-TIMP2 antibody [2C13] used in IHC (Paraffin sections) (IHC-P). GTX52487

Cat No. GTX52487

Host

Mouse

Clonality

Monoclonal

Clone Name

2C13

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:100 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes human TIMP-2 in western blot. No cross-reactivity to human TIMP-1 is noted.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant TIMP-2 protein

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CSC21K , DDC8 , TIMP metallopeptidase inhibitor 2 , TIMP2

Cellular Localization

Secreted

Background

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TIMP2 antibody [2C13] used in IHC (Paraffin sections) (IHC-P). GTX52487

GTX52487 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52487 TIMP2 antibody [2C13].

REFERENCE

There are currently no references for TIMP2 antibody [2C13] (GTX52487). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TIMP2 antibody [2C13] (GTX52487). Be the first to share your experience with this product.
SDS
PBS.pdf