GeneTex
United States (US)

TIMP2 antibody

GTX16392_20180530_ICCIF_18121410_746.jpg
GTX16392_20180530_WB_18121410_753.jpg

Cat No. GTX16392

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

24 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TIMP2 (NP_003246.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Timp Metallopeptidase Inhibitor 2,Csc-21K,Ddc8,Timp2

Background

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16392_20180530_ICCIF_18121410_746.jpg

GTX16392 ICC/IF Image

ICC/IF analysis of MCF-7 cell using GTX16392 TIMP2 antibody.
Blue : DAPI

GTX16392_20180530_WB_18121410_753.jpg

GTX16392 WB Image

WB analysis of various samples using GTX16392 TIMP2 antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:3000
Loading : 25μg per lane

REFERENCE
Package List Price ($)
$ 319