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TIRAP antibody [GT1343]

Recombinant antibody
Anti-TIRAP antibody [GT1343] used in Western Blot (WB). GTX03255
Anti-TIRAP antibody [GT1343] used in Western Blot (WB). GTX03255
Anti-TIRAP antibody [GT1343] used in IHC (Paraffin sections) (IHC-P). GTX03255
Anti-TIRAP antibody [GT1343] used in Western Blot (WB). GTX03255
Anti-TIRAP antibody [GT1343] used in IHC (Paraffin sections) (IHC-P). GTX03255

Cat. No. GTX03255

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1343

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($439)
See all TIRAP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.02 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human TIRAP.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TIR domain containing adaptor protein , BACTS1 , Mal , MyD88-2 , wyatt

Cellular Localization

Cytoplasm , Cell membrane , Membrane

Background

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TIRAP antibody [GT1343] used in Western Blot (WB). GTX03255

GTX03255 WB Image

Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TIRAP antibody [GT1343] (GTX03255) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TIRAP antibody [GT1343] used in Western Blot (WB). GTX03255

GTX03255 WB Image

Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TIRAP antibody [GT1343] (GTX03255) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TIRAP antibody [GT1343] used in IHC (Paraffin sections) (IHC-P). GTX03255

GTX03255 IHC-P Image

IHC-P analysis of rat lung tissue section using GTX03255 TIRAP antibody [GT1343].
Dilution : 1:100

Anti-TIRAP antibody [GT1343] used in Western Blot (WB). GTX03255

GTX03255 WB Image

WB analysis of various samples using GTX03255 TIRAP antibody [GT1343].
Dilution : 1:1000
Loading : 25μg per lane

Anti-TIRAP antibody [GT1343] used in IHC (Paraffin sections) (IHC-P). GTX03255

GTX03255 IHC-P Image

IHC-P analysis of mouse kidney tissue section using GTX03255 TIRAP antibody [GT1343].
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 439