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TKTL2 antibody [N1N3]

Anti-TKTL2 antibody [N1N3] used in Western Blot (WB). GTX118468
Anti-TKTL2 antibody [N1N3] used in Western Blot (WB). GTX118468
Anti-TKTL2 antibody [N1N3] used in Western Blot (WB). GTX118468

Cat. No. GTX118468

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all TKTL2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

Positive Control

293T , Mouse brain

Predict Reactivity

Rat, Bovine, Chimpanzee(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human TKTL2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10624801

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transketolase like 2

Background

Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Play a pivotal role in carcinogenesis.

Database

Research Area

DATA IMAGES

Anti-TKTL2 antibody [N1N3] used in Western Blot (WB). GTX118468

GTX118468 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse brain
7.5% SDS PAGE
GTX118468 diluted at 1:1000

Anti-TKTL2 antibody [N1N3] used in Western Blot (WB). GTX118468

GTX118468 WB Image

Sample (30 ug of whole cell lysate)
A: 293T
7.5% SDS PAGE
GTX118468 diluted at 1:2000

Anti-TKTL2 antibody [N1N3] used in Western Blot (WB). GTX118468

GTX118468 WB Image

The data was published in the journal J Exp Clin Cancer Res in 2019. PMID: 30971297

REFERENCE

Application Reference

Qin Z et al. J Exp Clin Cancer Res 2019; 38 (1) : 154 Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169