APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
Not tested in other applications.
Calculated MW
Positive Control
HeLa
Predict Reactivity
Mouse, Rat, Bovine, Chicken, Pig, Chimpanzee, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human TL1A. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_1952316
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
TNF superfamily member 15 , TL1 , TL1A , TNLG1B , VEGI , VEGI192A
Cellular Localization
Membrane; Single-pass type II membrane protein , Tumor necrosis factor ligand superfamily member 15 , secreted form: Secreted
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-TL1A antibody [C2C3], C-term used in Western Blot (WB). GTX108463](/templates/default/js/lightbox/images/loading.gif "Anti-TL1A antibody [C2C3], C-term used in Western Blot (WB). GTX108463")
|
GTX108463 WB Image
Sample (30 ug of whole cell lysate)
A: Hela
12% SDS PAGE
TL1A antibody
GTX108463 diluted at 1:1000
|
REFERENCE
There are currently no references for TL1A antibody [C2C3], C-term (GTX108463). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TL1A antibody [C2C3], C-term (GTX108463). Be the first to share your experience with this product.
![Anti-TL1A antibody [C2C3], C-term used in Western Blot (WB). GTX108463](/upload/website/prouct_img/small/GTX108463/GTX108463_WB_w_23060120_880.webp "Anti-TL1A antibody [C2C3], C-term used in Western Blot (WB). GTX108463")
![Anti-TL1A antibody [C2C3], C-term used in Western Blot (WB). GTX108463](/upload/website/prouct_img/normal/GTX108463/GTX108463_WB_w_23060120_880.webp "Anti-TL1A antibody [C2C3], C-term used in Western Blot (WB). GTX108463")