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TL1A antibody [VEGI/1283]

Anti-TL1A antibody [VEGI/1283] used in IHC (Paraffin sections) (IHC-P). GTX35124
Anti-TL1A antibody [VEGI/1283] used in IHC (Paraffin sections) (IHC-P). GTX35124

Cat. No. GTX35124

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 VEGI/1283

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all TL1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human VEGI fragment

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TL1 , TL1A , TNFSF15 , TNLG1B , VEGI , VEGI192A , tumor necrosis factor superfamily member 15 , TNFSF-15 , TNF superfamily member 15

Cellular Localization

Membrane,Secreted

Background

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-TL1A antibody [VEGI/1283] used in IHC (Paraffin sections) (IHC-P). GTX35124

GTX35124 IHC-P Image

IHC-P analysis of human parathyroid mass tissue using GTX35124 TL1A antibody [VEGI/1283].

Anti-TL1A antibody [VEGI/1283] used in IHC (Paraffin sections) (IHC-P). GTX35124

GTX35124 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX35124 TL1A antibody [VEGI/1283].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529