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TLR2 antibody [JM22-41]

Recombinant antibody
Anti-TLR2 antibody [JM22-41] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00996
Anti-TLR2 antibody [JM22-41] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00996
Anti-TLR2 antibody [JM22-41] used in IHC (Paraffin sections) (IHC-P). GTX00996
Anti-TLR2 antibody [JM22-41] used in Flow cytometry (FACS). GTX00996
Anti-TLR2 antibody [JM22-41] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00996
Anti-TLR2 antibody [JM22-41] used in IHC (Paraffin sections) (IHC-P). GTX00996

Cat No. GTX00996

Host

Rabbit

Clonality

Monoclonal

Clone Name

JM22-41

Isotype

IgG

Application

ICC/IF, IHC-P, FACS

Reactivity

Human, Mouse
Package
100 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1:50-1:200
IHC-P 1:50-1:200
FACS 1:50-1:100
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1x TBS (pH7.4), 1% BSA, 40% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

toll like receptor 2,CD282,TIL4,TLR2

Cellular Localization

Membrane,Cytoplasmic vesicle,Phagosome membrane,Membrane raft

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-TLR2 antibody [JM22-41] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00996

GTX00996 ICC/IF Image

ICC/IF analysis of PFA-fixed HepG2 cells using GTX00996 TLR2 antibody [JM22-41].
Green : primary antibody
Blue : DAPI
Permeabilization : 0.25% Triton X-100 in PBS

Anti-TLR2 antibody [JM22-41] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00996

GTX00996 ICC/IF Image

ICC/IF analysis of PFA-fixed PC-3M cells using GTX00996 TLR2 antibody [JM22-41].
Green : primary antibody
Blue : DAPI
Permeabilization : 0.25% Triton X-100 in PBS

Anti-TLR2 antibody [JM22-41] used in IHC (Paraffin sections) (IHC-P). GTX00996

GTX00996 IHC-P Image

IHC-P analysis of mouse spleen tissue section using GTX00996 TLR2 antibody [JM22-41].

Anti-TLR2 antibody [JM22-41] used in Flow cytometry (FACS). GTX00996

GTX00996 FACS Image

FACS analysis of THP-1 cells using GTX00996 TLR2 antibody [JM22-41].
Red : primary antibody
Black : unlabelled control
Dilution : 1:100

Anti-TLR2 antibody [JM22-41] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00996

GTX00996 ICC/IF Image

ICC/IF analysis of PFA-fixed A549 cells using GTX00996 TLR2 antibody [JM22-41].
Green : primary antibody
Blue : DAPI
Permeabilization : 0.25% Triton X-100 in PBS

Anti-TLR2 antibody [JM22-41] used in IHC (Paraffin sections) (IHC-P). GTX00996

GTX00996 IHC-P Image

IHC-P analysis of human spleen tissue section using GTX00996 TLR2 antibody [JM22-41].

REFERENCE

There are currently no references for TLR2 antibody [JM22-41] (GTX00996). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TLR2 antibody [JM22-41] (GTX00996). Be the first to share your experience with this product.