GeneTex
United States (US)

TLR2 antibody

GTX31279_882_IHC-P_20180221_18121410_525.jpg
GTX31279_881_IHC-P_20180221_18121410_760.jpg
GTX31279_2482_WB_20180221_18121410_201.jpg

Cat No. GTX31279

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

Positive Control

A20 Cell Lysate(GTX27180) , Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TLR2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TLR2.The immunogen is located within the first 50 amino acids of TLR2.

Purification

Purified by ion exchange chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Toll Like Receptor 2,Cd282,Til4,Tlr2

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31279_882_IHC-P_20180221_18121410_525.jpg

GTX31279 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31279 TLR2 antibody.
Working concentration : 2 μg/ml

GTX31279_881_IHC-P_20180221_18121410_760.jpg

GTX31279 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31279 TLR2 antibody.
Working concentration : 10 μg/ml

GTX31279_2482_WB_20180221_18121410_201.jpg

GTX31279 WB Image

WB analysis of A-20 cell lysates in the presence (A) and absence (B) of its blocking peptide using GTX31279 TLR2 antibody.
Working concentration : 1 μg/ml